1.What is White Kidney Bean Extract?

White kidney bean extract is a natural amylase inhibitor extracted from white kidney beans. Its main active ingredient is α-amylase inhibitory protein, which is found in the endosperm of white kidney bean seeds. This substance specifically binds to the glycoside site on the α-amylase molecule through its glycoprotein structure, causing a conformational change in the enzyme molecule and resulting in the loss of its catalytic activity, thus exhibiting a non-competitive inhibitory effect.


2.Regarding α-amylase inhibition：

White kidney bean extract is a natural starch inhibitor that works through a specific mechanism: the bean protein it contains can reversibly bind to the active site of α-amylase, inhibiting it by 65-85%, thus preventing starch from breaking down into absorbable monosaccharides. α-amylase inhibitors are a class of natural bioactive substances that specifically inhibit α-amylase activity, mainly derived from Streptomyces microorganisms and the seeds of cereals and legumes; their structures include oligosaccharides and proteins. By blocking amylase activity without inhibiting β-amylase and β-glucosidase, it delays starch digestion and is used in diabetes management and weight control. Typical sources include white kidney bean extract (containing bean protein) and Poria cocos triterpenoid extract (IC50 value 10.43 μg/mL). This inhibitor also has potential applications in genetically modified insect-resistant crops and has been developed as a dietary supplement.


3.Function：

1. Inhibits Starch Digestion and Weight Management (Core Benefits)

• Reduces Calorie Absorption: Prevents approximately 66% of the starch in ingested complex carbohydrates from being digested and absorbed, allowing it to be directly excreted through the intestines;

• Reduces Glycemic Response: Significantly delays the rise in postprandial blood glucose, reducing peak blood glucose levels by 20-40%, and minimizing blood glucose fluctuations;

• Clinical Efficacy: Multiple studies have shown that daily intake of 445-3000mg of white kidney bean extract, combined with a balanced diet, can help with weight loss of 2-4 kg and a waist circumference reduction of 2-6 cm within 8-12 weeks;

4.Application：
* Nutrition and Pharmaceutical Industry: Regular compressed tablets, coated tablets, sugar-coated tablets, hard capsules, soft capsules, topical gels, granules, etc.

* Food and Beverage Industry: Water-soluble solid beverages, instant beverages, chewable tablets, compressed candies, low-G